Infectious agents in juvenile scleroderma

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Infectious agents in juvenile scleroderma

Introduction The problem of juvenile scleroderma (JS) is determined by a variety of clinical manifestations, tendency to early generalized process with the development of peripheral and visceral lesions. In the last decade various forms JS associated with Borrelia infection, as evidenced by the discovery of a skin biopsy patients spirochete Borrelia Burgdorferii afzelii, garinii and the presenc...

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PReS13-SPK-1469: Juvenile scleroderma

Juvenile localized scleroderma, also known as morphea, is the more frequent subtype of scleroderma in childhood. It comprises a group of distinct conditions which involve the skin and subcutaneous tissues. They range from very small plaques of fibrosis involving only the skin, to diseases which may cause significant functional and cosmetic deformity. The most widely used classification divides ...

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Juvenile scleroderma: experience in one institution.

BACKGROUND Scleroderma is a chronic connective tissue disease characterized by hardened or scaly skin and widespread abnormalities of the viscera, which is rare in the pediatric age group. OBJECTIVE In this study, we retrospectively reviewed 23 pediatric patients suffering systemic (SSc) and localized (LS) scleroderma. METHODS Twenty-three patients were enrolled and were diagnosed with SSc ...

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Juvenile localized scleroderma: review of 44 patients

Results 70.5% of patients were females. CM (34.1%) and LM (34.1%) were the most frequently subtypes. Mean age at first symptoms was 7.7 years (Figure 1). Medium time between first signs/symptoms and diagnosis was 15.42 months. One patient with CM head-neck lesions had Parry-Romberg disease with neurological involvement. 50% of patients with head-neck LM had “coup de sabre” subtype, 25% of that ...

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PReS-FINAL-2120: Juvenile scleroderma international network (JUSINET) database: a reliable instrument for clinical research in juvenile scleroderma syndromes

Objectives We propose a web-based registry (http://www.jusinet. org) to prospectively collect data on demographic, epidemiological, clinical, and laboratory features of patients with jssc and JLS from adult and paediatric rheumatology centres and to educate physicians to a more standardized approach to these conditions. The purpose is to provide a well-characterized cohort of scleroderma patien...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2014

ISSN: 1546-0096

DOI: 10.1186/1546-0096-12-s1-p306